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Study of the anti-inflammatory mechanism of -carotene based on network pharmacology

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To this regard, the intake of vitamins C and E is sufficient to reduce the positive effects of exercise via ROS-related induction of PPAR, PGC1, and PGC1, as well as the ROS-detoxifying enzymes, indicating that the removal of ROS can reduce, or even inhibit, the health benefits of exercise (Ristow et al., 2009)