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Pizzorno Jr., ND, is a leading authority on science-based natural and integrative medicine

Supplementary Table 7 (download XLSX List of primers and oligonucleotides used in this study

Proteomic analysis has shown that x-ray repair cross-complementing protein 1 (XRCC1) K247 lactylation enhances its binding affinity for importin- (also known as Karyopherin-), facilitating nuclear translocation and promoting DNA damage repair in tumor cells

Abstract Despite advances in immunotherapy, triple-negative breast cancer (TNBC) remains a major therapeutic challenge owing to its marked aggressiveness, low immunogenicity, and limited responsiveness to immune checkpoint blockade (ICB)